Magnetic Resonance Spectroscopy in Diagnosis and Follow-Up of Gliomas: State-of-the-Art

Author:

Galijasevic MalikORCID,Steiger RuthORCID,Mangesius StephanieORCID,Mangesius JulianORCID,Kerschbaumer JohannesORCID,Freyschlag Christian FranzORCID,Gruber NadjaORCID,Janjic TanjaORCID,Gizewski Elke RuthORCID,Grams Astrid EllenORCID

Abstract

Preoperative grade prediction is important in diagnostics of glioma. Even more important can be follow-up after chemotherapy and radiotherapy of high grade gliomas. In this review we provide an overview of MR-spectroscopy (MRS), technical aspects, and different clinical scenarios in the diagnostics and follow-up of gliomas in pediatric and adult populations. Furthermore, we provide a recap of the current research utility and possible future strategies regarding proton- and phosphorous-MRS in glioma research.

Publisher

MDPI AG

Subject

Cancer Research,Oncology

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