Malignant Acute Colonic Obstruction: Multidisciplinary Approach for Endoscopic Management

Author:

Mauro Aurelio1ORCID,Scalvini Davide12,Borgetto Sabrina3,Fugazzola Paola4,Mazza Stefano1ORCID,Perretti Ilaria5ORCID,Gallotti Anna5ORCID,Pagani Anna3,Ansaloni Luca4ORCID,Anderloni Andrea1ORCID

Affiliation:

1. Gastroenterology and Endoscopy Unit, Fondazione IRCCS Policlinico San Matteo, Viale Camillo Golgi 19, 27100 Pavia, Italy

2. Department of Internal Medicine, PhD in Experimental Medicine Italy, University of Pavia, 27100 Pavia, Italy

3. Medical Oncology Unit, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy

4. Department of General Surgery, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy

5. Institute of Radiology, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy

Abstract

Patients presenting with acute colonic obstruction are usually evaluated in the emergency department and multiple specialties are involved in the patients’ management. Pre-treatment evaluation is essential in order to establish the correct endoscopic indication for stent implantation. Contrast-enhanced imaging could allow the exclusion of benign causes of colonic obstruction and evaluation of the length of malignant stricture. Endoscopic stenting is the gold standard of treatment for palliative indications whereas there are still concerns about its use as a bridge to surgery. Different meta-analyses showed that stenting as a bridge to surgery improves short-term surgical outcomes but has no role in improving long-term outcomes. Multidisciplinary evaluation is also essential in patients that may be started on or are currently receiving antiangiogenic agents because endoscopic stenting may increase the risk of perforation. Evidence in the literature is weak and based on retrospective data. Here we report on how to correctly evaluate a patient with acute colonic malignant obstruction in collaboration with other essential specialists including a radiologist, surgeon and oncologist, and how to optimize the technique of endoscopic stenting.

Publisher

MDPI AG

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