Automatic Segmentation with Deep Learning in Radiotherapy

Author:

Isaksson Lars Johannes12ORCID,Summers Paul3ORCID,Mastroleo Federico14ORCID,Marvaso Giulia1ORCID,Corrao Giulia1ORCID,Vincini Maria Giulia1ORCID,Zaffaroni Mattia1ORCID,Ceci Francesco25ORCID,Petralia Giuseppe26,Orecchia Roberto7,Jereczek-Fossa Barbara Alicja12

Affiliation:

1. Division of Radiation Oncology, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy

2. Department of Oncology and Hemato-Oncology, University of Milan, 20141 Milan, Italy

3. Division of Radiology, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy

4. Department of Translational Medicine, University of Piemonte Orientale (UPO), 20188 Novara, Italy

5. Division of Nuclear Medicine, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy

6. Precision Imaging and Research Unit, Department of Medical Imaging and Radiation Sciences, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy

7. Scientific Directorate, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy

Abstract

This review provides a formal overview of current automatic segmentation studies that use deep learning in radiotherapy. It covers 807 published papers and includes multiple cancer sites, image types (CT/MRI/PET), and segmentation methods. We collect key statistics about the papers to uncover commonalities, trends, and methods, and identify areas where more research might be needed. Moreover, we analyzed the corpus by posing explicit questions aimed at providing high-quality and actionable insights, including: “What should researchers think about when starting a segmentation study?”, “How can research practices in medical image segmentation be improved?”, “What is missing from the current corpus?”, and more. This allowed us to provide practical guidelines on how to conduct a good segmentation study in today’s competitive environment that will be useful for future research within the field, regardless of the specific radiotherapeutic subfield. To aid in our analysis, we used the large language model ChatGPT to condense information.

Publisher

MDPI AG

Subject

Cancer Research,Oncology

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