The Impact of Urine-Sample HPV Testing on the Effectiveness of Screening for Cervical Cancer: An Umbrella Review

Author:

Miazga Wojciech1ORCID,Tatara Tomasz2ORCID,Wnuk Katarzyna1ORCID,Gujski Mariusz2,Pinkas Jarosław1ORCID,Religioni Urszula1ORCID

Affiliation:

1. School of Public Health, Centre of Postgraduate Medical Education of Warsaw, Kleczewska 61/63, 01-826 Warsaw, Poland

2. Department of Public Health, Faculty of Health Sciences, Medical University of Warsaw, Żwirki i Wigury 61, 02-091 Warsaw, Poland

Abstract

Background: The aim of the study was to evaluate the impact of urine-sample HPV (human papillomavirus) testing on the effectiveness of screening for cervical cancer. Methods: The analysis was based on the results of a systematic review. Secondary studies were searched in the following medical databases: Medline, Embase, and the Cochrane Library. The results of the statistical tests presented in the article originate from research conducted by the authors of the included articles. Results: From a total of 1869 citations, 5 studies were included in this review. Sensitivity and specificity for the detection of any HPV from first-void urine samples were 87% [95% CI: (0.74; 0.94)] and 89% [95% CI: (0.81; 0.93)], respectively. Moreover, participants in the analyzed studies had indicated that they felt comfortable with urine testing. Conclusions: The development of methods to detect HPV infection in first-void urine samples and the application of this sampling method in widely available screening tests could significantly increase patients’ willingness to participate in testing.

Publisher

MDPI AG

Reference18 articles.

1. Ferlay, J., Ervik, M., Lam, F., Laversanne, M., and Colombet, M. (2024, March 07). Global Cancer Observatory: Cancer Today. Lyon, France: International Agency for Research on Cancer. Available online: https://gco.iarc.who.int/today.

2. Meites, E., Gee, J., Unger, E., and Markowitz, L. (2024, March 07). Human Papillomavirus, Available online: https://www.cdc.gov/vaccines/pubs/pinkbook/downloads/hpv.pdf.

3. World Health Organization (2020). Global Strategy to Accelerate the Elimination of Cervical Cancer as a Public Health Problem, World Health Organization. Licence: CC BY-NC-SA 3.0 IGO.

4. National Cancer Institute 2023 (2024, March 07). Cervical Cancer Screening, Available online: https://www.cancer.gov/types/cervical/screening.

5. Tatara, T., Wnuk, K., Miazga, W., Świtalski, J., Karauda, D., Mularczyk-Tomczewska, P., Religioni, U., and Gujski, M. (2022). The Influence of Vaginal HPV Self-Sampling on the Efficacy of Populational Screening for Cervical Cancer—An Umbrella Review. Cancers, 14.

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