Radiomics Applications in Head and Neck Tumor Imaging: A Narrative Review

Author:

Tortora Mario1ORCID,Gemini Laura1,Scaravilli Alessandra1ORCID,Ugga Lorenzo1ORCID,Ponsiglione Andrea1,Stanzione Arnaldo1ORCID,D’Arco Felice2ORCID,D’Anna Gennaro3ORCID,Cuocolo Renato14ORCID

Affiliation:

1. Department of Advanced Biomedical Sciences, University of Naples “Federico II”, 80131 Naples, Italy

2. Department of Radiology, Neuroradiology Unit, Great Ormond Street Hospital, London WC1N 3JH, UK

3. Neuroimaging Unit, ASST Ovest Milanese, 20025 Legnano, Italy

4. Department of Medicine, Surgery and Dentistry, University of Salerno, 84081 Baronissi, Italy

Abstract

Recent advances in machine learning and artificial intelligence technology have ensured automated evaluation of medical images. As a result, quantifiable diagnostic and prognostic biomarkers have been created. We discuss radiomics applications for the head and neck region in this paper. Molecular characterization, categorization, prognosis and therapy recommendation are given special consideration. In a narrative manner, we outline the fundamental technological principles, the overall idea and usual workflow of radiomic analysis and what seem to be the present and potential challenges in normal clinical practice. Clinical oncology intends for all of this to ensure informed decision support for personalized and useful cancer treatment. Head and neck cancers present a unique set of diagnostic and therapeutic challenges. These challenges are brought on by the complicated anatomy and heterogeneity of the area under investigation. Radiomics has the potential to address these barriers. Future research must be interdisciplinary and focus on the study of certain oncologic functions and outcomes, with external validation and multi-institutional cooperation in order to achieve this.

Publisher

MDPI AG

Subject

Cancer Research,Oncology

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