Tumor Models and Drug Targeting In Vitro—Where Are We Today? Where Do We Go from Here?

Author:

Krüger Marcus1ORCID,Kopp Sascha2ORCID

Affiliation:

1. Environmental Cell Biology Group, Department of Microgravity and Translational Regenerative Medicine, Otto von Guericke University, 39106 Magdeburg, Germany

2. Core Facility Tissue Engineering, Otto von Guericke University, 39106 Magdeburg, Germany

Abstract

Cancer is one of the leading causes of death worldwide [...]

Publisher

MDPI AG

Subject

Cancer Research,Oncology

Reference30 articles.

1. Three-dimensional cell culture: A powerful tool in tumor research and drug discovery;Lv;Oncol. Lett.,2017

2. From bench to bedside: Does preclinical practice in translational oncology need some rebuilding?;Bertotti;J. Natl. Cancer Inst.,2013

3. What’s wrong with our cancer models?;Kamb;Nat. Rev. Drug Discov.,2005

4. Three-dimensional models of cancer for pharmacology and cancer cell biology: Capturing tumor complexity in vitro/ex vivo;Hickman;Biotechnol. J.,2014

5. The third dimension bridges the gap between cell culture and live tissue;Pampaloni;Nat. Rev. Mol. Cell Biol.,2007

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