Role of Ubiquitin Ligases and Conjugases in Targeted Cancer Therapy

Author:

Vriend Jerry1

Affiliation:

1. Department of Human Anatomy and Cell Science, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB R3E 0J9, Canada

Abstract

The ubiquitin proteasome system regulates the activity of many short-lived proteins in cells [...]

Publisher

MDPI AG

Subject

Cancer Research,Oncology

Reference27 articles.

1. The ubiquitin system;Hershko;Annu. Rev. Biochem.,1998

2. Screening and predicted value of potential biomarkers for breast cancer using bioinformatics analysis;Zeng;Sci. Rep.,2021

3. E3 ligase RNF167 and deubiquitinase STAMBPL1 modulate mTOR and cancer progression;Wang;Mol. Cell,2022

4. Screening key genes and signaling pathways in colorectal cancer by integrated bioinformatics analysis;Yu;Mol. Med. Rep.,2019

5. Ubiquitin conjugating enzyme E2 C (UBE2C) may play a dual role involved in the progression of thyroid carcinoma;Xiang;Cell. Death Discov.,2022

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