Application of PET/MRI in Gynecologic Malignancies

Author:

Ebrahimi Sheida1ORCID,Lundström Elin123,Batasin Summer J.1,Hedlund Elisabeth2,Stålberg Karin4ORCID,Ehman Eric C.5,Sheth Vipul R.6,Iranpour Negaur6,Loubrie Stephane1,Schlein Alexandra1,Rakow-Penner Rebecca17ORCID

Affiliation:

1. Department of Radiology, University of California San Diego, La Jolla, CA 92093, USA

2. Department of Surgical Sciences, Radiology, Uppsala University, 751 85 Uppsala, Sweden

3. Center for Medical Imaging, Uppsala University Hospital, 751 85 Uppsala, Sweden

4. Department of Women’s and Children’s Health, Uppsala University, 751 85 Uppsala, Sweden

5. Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA

6. Department of Radiology, Stanford University, Palo Alto, CA 94305, USA

7. Department of Bioengineering, University of California San Diego, La Jolla, CA 92093, USA

Abstract

The diagnosis, treatment, and management of gynecologic malignancies benefit from both positron emission tomography/computed tomography (PET/CT) and MRI. PET/CT provides important information on the local extent of disease as well as diffuse metastatic involvement. MRI offers soft tissue delineation and loco-regional disease involvement. The combination of these two technologies is key in diagnosis, treatment planning, and evaluating treatment response in gynecological malignancies. This review aims to assess the performance of PET/MRI in gynecologic cancer patients and outlines the technical challenges and clinical advantages of PET/MR systems when specifically applied to gynecologic malignancies.

Funder

NIH

GE Healthcare

Krueger v. Wyeth Research Award

Swedish Research Council

Lions Cancer Fund Mellansverige Uppsala-Örebro

Makarna Eriksson Foundation

Urogenital Radiology Fellowship of the European School of Radiology (ESOR)/European Society of Urogenital Radiology

Publisher

MDPI AG

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