No Geographical Inequalities in Survival for Sarcoma Patients in France: A Reference Networks’ Outcome?
Author:
Fayet YohanORCID, Chevreau Christine, Decanter Gauthier, Dalban Cécile, Meeus Pierre, Carrère Sébastien, Haddag-Miliani Leila, Le Loarer FrançoisORCID, Causeret Sylvain, Orbach DanielORCID, Kind Michelle, Le Nail Louis-Romée, Ferron Gwenaël, Labrosse Hélène, Chaigneau Loïc, Bertucci FrançoisORCID, Ruzic Jean-Christophe, Le Brun Ly Valérie, Farsi Fadila, Bompas Emmanuelle, Noal Sabine, Vozy Aurore, Ducoulombier Agnes, Bonnet Clément, Chabaud Sylvie, Ducimetière FrançoiseORCID, Tlemsani CamilleORCID, Ropars Mickaël, Collard Olivier, Michelin PaulORCID, Gantzer Justine, Dubray-Longeras Pascale, Rios Maria, Soibinet Pauline, Le Cesne Axel, Duffaud Florence, Karanian Marie, Gouin François, Tétreau Raphaël, Honoré Charles, Coindre Jean-Michel, Ray-Coquard IsabelleORCID, Bonvalot SylvieORCID, Blay Jean-YvesORCID
Abstract
The national reference network NETSARC+ provides remote access to specialized diagnosis and the Multidisciplinary Tumour Board (MTB) to improve the management and survival of sarcoma patients in France. The IGéAS research program aims to assess the potential of this innovative organization to address geographical inequalities in cancer management. Using the IGéAS cohort built from the nationwide NETSARC+ database, the individual, clinical, and geographical determinants of the 3-year overall survival of sarcoma patients in France were analyzed. The survival analysis was focused on patients diagnosed in 2013 (n = 2281) to ensure sufficient hindsight to collect patient follow-up. Our study included patients with bone (16.8%), soft-tissue (69%), and visceral (14.2%) sarcomas, with a median age of 61.8 years. The overall survival was not associated with geographical variables after adjustment for individual and clinical factors. The lower survival in precarious population districts [HR 1.23, 95% CI 1.02 to 1.48] in comparison to wealthy metropolitan areas (HR = 1) found in univariable analysis was due to the worst clinical presentation at diagnosis of patients. The place of residence had no impact on sarcoma patients’ survival, in the context of the national organization driven by the reference network. Following previous findings, this suggests the ability of this organization to go through geographical barriers usually impeding the optimal management of cancer patients.
Funder
Fondation ARC pour la Recherche sur le Cancer French National Cancer Institute SIRIC LYriCAN
Subject
Cancer Research,Oncology
Cited by
3 articles.
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