Health-Related Quality of Life and Return to Work after Surgery for Spinal Schwannoma: A Population-Based Cohort Study

Author:

Singh Aman12ORCID,von Vogelsang Ann-Christin1,El-Hajj Victor Gabriel1ORCID,Buwaider Ali1ORCID,Fletcher-Sandersjöö Alexander13,Pettersson-Segerlind Jenny13,Edström Erik145ORCID,Elmi-Terander Adrian1245ORCID

Affiliation:

1. Department of Clinical Neuroscience, Karolinska Institute, 171 76 Stockholm, Sweden

2. Department of Surgical Sciences, Uppsala University, 752 36 Uppsala, Sweden

3. Department of Neurosurgery, Karolinska University Hospital, 171 76 Stockholm, Sweden

4. Sweden Capio Spine Center Stockholm, Löwenströmska Hospital, 194 89 Upplands-Väsby, Sweden

5. Department of Medical Sciences, Örebro University, 701 82 Örebro, Sweden

Abstract

Spinal schwannomas are the second most common primary intradural spinal tumor. This study aimed to assess health-related quality of life (HRQoL) and the frequency of return to work after the surgical treatment of spinal schwannomas. HRQoL was compared to a sample of the general population. Patients operated for spinal schwannomas between 2006 and 2020 were identified in a previous study and those alive at follow-up (171 of 180) were asked to participate. Ninety-four (56%) responded and were included in this study. Data were compared to the Stockholm Public Health Survey 2006, a cross-sectional survey of a representative sample of the general population. An analysis for any potential non-response bias was performed and showed no significant differences between the groups. HRQoL was equal between the spinal schwannoma sample and the general population sample in all but one dimension; men in the spinal schwannoma sample reported more moderate problems in the usual activities dimension than men in the general population (p = 0.020). In the schwannoma sample, there were no significant differences between men and women in either of the dimensions EQ-5Dindex or EQVAS. Before surgery, a total of 71 (76%) were working full-time and after surgery almost all (94%) returned to work, most of them within 3 months of surgery. Eighty-nine (95%) of the patients responded that they would accept the surgery for their spinal schwannoma if asked again today. To conclude, surgical treatment of spinal schwannomas is associated with good HRQoL and with a high frequency of return to work.

Publisher

MDPI AG

Reference38 articles.

1. Singh, A., Fletcher-Sandersjoo, A., El-Hajj, V.G., Burstrom, G., Edstrom, E., and Elmi-Terander, A. (2024). Long-Term Functional Outcomes Following Surgical Treatment of Spinal Schwannomas: A Population-Based Cohort Study. Cancers, 16.

2. Long-term Surgical Outcomes of Spinal Schwannomas: Retrospective Analysis of 49 Consecutive Cases;Emel;Turk. Neurosurg.,2017

3. The 2016 World Health Organization Classification of Tumors of the Central Nervous System: A summary;Louis;Acta Neuropathol.,2016

4. Surgical management of malignant melanotic nerve sheath tumors: An institutional experience and systematic review of the literature;Ghaith;J. Neurosurg. Spine,2024

5. Neurological outcome after resection of spinal schwannoma;Hohenberger;Clin. Neurol. Neurosurg.,2020

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1. Predictors of return to work after spinal surgery : systematic review and Meta-analysis;Journal of Orthopaedic Surgery and Research;2024-08-24

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