Helicobacter pylori Infection in Patients with Gastric Cancer: A 2024 Update

Author:

Burz Claudia12ORCID,Pop Vlad1,Silaghi Ciprian3ORCID,Lupan Iulia45,Samasca Gabriel2ORCID

Affiliation:

1. Institute of Oncology “Prof. Ion Chiricuta”, 400015 Cluj-Napoca, Romania

2. Department of Immunology, Iuliu Hatieganu University of Medicine and Pharmacy, 400162 Cluj-Napoca, Romania

3. Department of Biochemistry, Iuliu Hatieganu University of Medicine and Pharmacy, 400349 Cluj-Napoca, Romania

4. Institute for Interdisciplinary Research in Bio-Nanosciences, 400271 Cluj-Napoca, Romania

5. Department of Molecular Biology, Babes-Bolyai University, 400084 Cluj-Napoca, Romania

Abstract

Numerous studies have been performed on Helicobacter pylori infection because of the high death rate linked to this illness and gastric cancer. An update on the key developments in recent years in the investigation of Helicobacter pylori and gastric cancer is the goal of this review. Using the search term “Helicobacter pylori, gastric cancer”, the PubMed database was searched. Only papers published in 2024 fulfilled the inclusion criteria. Because case report papers were not part of our investigation, they satisfied the exclusion criteria. Most of the research on the variable genes of Helicobacter pylori is guided by genetics to determine potential treatments. Studies on clinical treatments for the eradication of H. pylori with promising therapeutic options are needed. We found the fewest studies related to the immunopathology of H. pylori infection, which is still unknown. In conclusion, priority should be given to this kind of research.

Publisher

MDPI AG

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