Neoadjuvant Chemotherapy in Breast Cancer: Evaluation of the Impact on Surgical Outcomes and Prognosis-Reference-Cited by-同舟云学术

Neoadjuvant Chemotherapy in Breast Cancer: Evaluation of the Impact on Surgical Outcomes and Prognosis

Published:2024-06-26 Issue:13 Volume:16 Page:2332
ISSN:2072-6694
Container-title:Cancers
language:en
Short-container-title:Cancers

Author:

Chiappa Corrado¹^ORCID,Greta Maltecca¹,Miriam Leoni¹,Ietto Giuseppe²^ORCID,Inversini Davide²,Ballabio Andrea²,Bonetti Alice¹,Mangano Alberto³,Gueli Rossana⁴^ORCID,Carcano Giulio²^ORCID,Rovera Francesca Angela¹

Affiliation:

1. Senology Research Center, Department of Medicine and Innovation Technology (DiMIT), University of Insubria, 21100 Varese, Italy

2. Department of Medicine and Innovation Technology (DiMIT), University of Insubria, 21100 Varese, Italy

3. Division of General, Minimally Invasive and Robotic Surgery, University of Illinois at Chicago, 840 S Wood Street, Suite 435 E, Clinical Sciences Building, Chicago, IL 60612, USA

4. Oncology Unit, ASST-Sette Laghi, 21100 Varese, Italy

Abstract

The correlation between TNM staging and histology variations in a sample of patients who underwent neoadjuvant chemotherapy demonstrates a positive impact on both increasing conservative surgery and achieving pCR, resulting in better outcomes in terms of disease-free survival (DFS) and the risk of relapse. Benefits have also been highlighted in terms of cosmetic outcomes, postoperative complications, and psychological benefits. However, the overall outcomes must be evaluated according to the subtype and individual characteristics of the patients.

Publisher

MDPI AG

Link

https://www.mdpi.com/2072-6694/16/13/2332/pdf

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