Cancer and Cardiovascular Disease: The Conjoined Twins

Author:

Zmaili Mohammad1ORCID,Alzubi Jafar2,Alkhayyat Motasem3,Albakri Almaza4,Alkhalaileh Feras5,Longinow Joshua5,Moudgil Rohit15

Affiliation:

1. Robert and Suzanne Tomsich Department of Cardiovascular Medicine, Sydell and Arnold Miller Family Heart, Vascular and Thoracic Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA

2. Department of Medicine, Division of Cardiology, Einstein Medical Center, Philadelphia, PA 19141, USA

3. Department of Gastroenterology, Hepatology and Nutrition, Digestive Disease and Surgery Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA

4. Jordanian Royal Medical Services, Department of Internal Medicine, King Abdullah II Ben Al-Hussein Street, Amman 11855, Jordan

5. Department of Internal Medicine, Cleveland Clinic, Cleveland, OH 44195, USA

Abstract

Cancer and cardiovascular disease are the two most common causes of death worldwide. As the fields of cardiovascular medicine and oncology continue to expand, the area of overlap is becoming more prominent demanding dedicated attention and individualized patient care. We have come to realize that both fields are inextricably intertwined in several aspects, so much so that the mere presence of one, with its resultant downstream implications, has an impact on the other. Nonetheless, cardiovascular disease and cancer are generally approached independently. The focus that is granted to the predominant pathological entity (either cardiovascular disease or cancer), does not allow for optimal medical care for the other. As a result, ample opportunities for improvement in overall health care are being overlooked. Herein, we hope to shed light on the interconnected relationship between cardiovascular disease and cancer and uncover some of the unintentionally neglected intricacies of common cardiovascular therapeutics from an oncologic standpoint.

Publisher

MDPI AG

Reference253 articles.

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3. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA;Bray;Cancer J. Clin.,2018

4. Deaths: Final data for 2019;Xu;Natl. Vital Stat. Rep.,2021

5. The World Health Organization (WHO) (2021). Cardiovascular Diseases (CVDs), WHO.

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