Steady-State Delivery and Chemical Modification of Food Nutrients to Improve Cancer Intervention Ability

Author:

Hao Sijia1234,Ge Peng1234,Su Wentao1234ORCID,Wang Yuxiao1234,Abd El-Aty A. M.56,Tan Mingqian1234ORCID

Affiliation:

1. State Key Laboratory of Marine Food Processing and Safety Control, Dalian Polytechnic University, Dalian 116034, China

2. Academy of Food Interdisciplinary Science, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, China

3. National Engineering Research Center of Seafood, Dalian Polytechnic University, Dalian 116034, China

4. Dalian Key Laboratory for Precision Nutrition, Dalian Polytechnic University, Dalian 116034, China

5. Department of Pharmacology, Faculty of Veterinary Medicine, Cairo University, Giza 12211, Egypt

6. Department of Medical Pharmacology, Medical Faculty, Ataturk University, Erzurum 25240, Turkey

Abstract

Cancer is a crucial global health problem, and prevention is an important strategy to reduce the burden of the disease. Daily diet is the key modifiable risk factor for cancer, and an increasing body of evidence suggests that specific nutrients in foods may have a preventive effect against cancer. This review summarizes the current evidence on the role of nutrients from foods in cancer intervention. It discusses the potential mechanisms of action of various dietary components, including phytochemicals, vitamins, minerals, and fiber. The findings of epidemiological and clinical studies on their association with cancer risk are highlighted. The foods are rich in bioactive compounds such as carotenoids, flavonoids, and ω-3 fatty acids, which have been proven to have anticancer properties. The effects of steady-state delivery and chemical modification of these food’s bioactive components on anticancer and intervention are summarized. Future research should focus on identifying the specific bioactive compounds in foods responsible for their intervention effects and exploring the potential synergistic effects of combining different nutrients in foods. Dietary interventions that incorporate multiple nutrients and whole foods may hold promise for reducing the risk of cancer and improving overall health.

Funder

National Key Research and Development Program of China

National Science Fund for Distinguished Young Scholars of China

China Postdoctoral Science Foundation

Dalian Science and Technology Talent Innovation Support Program

Publisher

MDPI AG

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