A Literature Review of the Pharmacological Effects of Jujube

Author:

Zhu Deqi1,Jiang Ning2ORCID,Wang Ning1ORCID,Zhao Yufen1,Liu Xinmin12

Affiliation:

1. Institute of Drug Discovery Technology, Ningbo University, Ningbo 315211, China

2. Research Center for Pharmacology and Toxicology, Institute of Medicinal Plant Development (IMPLAD), Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China

Abstract

Jujube is a plant native to China that could be used in medicine and food. Its dried fruit is a superior herb commonly used in traditional Chinese medicine formulations for its calming effect and for nourishing the blood and strengthening the spleen and stomach. Jujube contains numerous active components including polysaccharides, phenols, and triterpene acids, which show a diverse array of pharmacological activities such as neuroprotection and the prevention and treatment of cardiovascular diseases. In this paper, the research status of jujube over the past two decades has been statistically evaluated. Meanwhile, by tracking the latest research advances, the pharmacological efficacy and molecular mechanisms of jujube are exhaustively expounded to provide specific and systematic references for further research on the pharmacological effects of jujube and its application in the food and pharmaceutical industries.

Funder

International Cooperative Project of Traditional Chinese Medicine

Innovation Fund for Medical Sciences

Space Medical Experiment Project of the China Manned Space Program

Publisher

MDPI AG

Reference81 articles.

1. A comparative plastomic analysis of Ziziphus jujuba var. spinosa (Bunge) Hu ex H. F. Chow and implication of the origin of Chinese jujube;Du;AoB Plants,2023

2. Li, H., Liang, L., and Li, X. (2014). Treatise on Typhoid and Miscellaneous Diseases, Beijing Science and Technology Press.

3. Yang, S.S., Xiao, Y.P., Wang, H.T., and Li, Y. (1955). Yellow Emperor’s Classic of Internal Medicine, People’s Medical Publishing House.

4. Gu, G.G. (2004). Shennong’s Herbal, Lanzhou University Press.

5. Quantitative assessment of bioactive compounds and the antioxidant activity of 15 jujube cultivars;Kou;Food Chem.,2015

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