Affiliation:
1. Department of Chemistry, Mississippi State University, Mississippi State, MS 39762, USA
Abstract
(4-(Adamantan-1-yl)-1-(isopropyl)-1H-imidazol-2-yl)methanol was prepared through a five-step process starting from commercially available 1-acetyladamantane. Each step proceeded in moderate-to-excellent yields and the overall yield across five steps was 28%. The compound was identified and characterized by 1H and 13C{1H} NMR, high-resolution mass spectroscopy, and elemental analysis. This compound and its derivatives have the potential to be used as precursors to the synthesis of biomimetic chelating ligands.
Funder
The National Institute for General Medical Sciences
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry