Abstract
In the mammalian neocortex, the calcium-binding protein
calretinin is expressed in a subset of cortical interneurons. In the
recent years, research on interneurons is one of the most rapidly
growing fields in neuroscience. This review summarizes the
actual knowledge of the functions of calretinin in neuronal
homeostasis and particularly of the distribution, connectivity and
physiological properties of calretinin expressing interneurons in
the neocortex of rodents and primates, including humans. The
possible neuroprotective role of calretinin and the presumed
“resistance” of calretinin-expressing interneurons to various
pathological processes are also discussed.
Publisher
Institute of Physiology of the Czech Academy of Sciences
Subject
General Medicine,Physiology
Cited by
108 articles.
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