Involvement of Membrane Fluidity in Endogenous Protective Processes Running on Subcellular Membrane Systems of the Rat Heart-Reference-Cited by-同舟云学术

Involvement of Membrane Fluidity in Endogenous Protective Processes Running on Subcellular Membrane Systems of the Rat Heart

Published:2012-10-19 Issue: Volume: Page:S11-S21
ISSN:1802-9973
Container-title:Physiological Research
language:en
Short-container-title:Physiol Res

Author:

ZIEGELHÖFFER A.¹,WACZULÍKOVÁ I.,FERKO M.,ŠIKUROVÁ L.,MUJKOŠOVÁ J.,RAVINGEROVÁ T.

Affiliation:

1. Institute for Heart Research, Slovak Academy of Sciences and Centre of Excellence, Slovak Academy of Sciences, NO REG, Bratislava, Slovakia

Abstract

Membrane fluidity is a widely recognized biophysical variable that provides information about structural organization of the subcellular membranes exhibiting physical characteristics of liquid crystals. The term “fluidity” reflects in this case the tightness in packing of acyl parts of the membrane phospholipid molecules, a feature that may influence considerably the molecular mobility and via that also the sensitivity and reactivity of membrane-bound transporters, receptors and enzyme systems. Data presented in this review are aimed to demonstrate the substantial role of changes in membrane fluidity occurring in the processes associated with endogenous protection observed in cardiac sarcolemma and mitochondria in diverse pathologies, particularly in diabetes and hypertension.

Publisher

Institute of Physiology of the Czech Academy of Sciences

Subject

General Medicine,Physiology

Reference52 articles.

1. BAKKER A, BERNAERT I, DE BIE M, RAVINGEROVA T, ZIEGELHÖFFER A, VAN BELLE H, JACOB W: The effect of calcium on mitochondrial contact sites: a study on isolated rat hearts. Biochim Biophys Acta 1224: 583-588, 1994.

2. BARENHOLZ Y, COHEN T, HAAS E, OTTOLENGHI M: Lateral organization of pyrene-labeled lipids in bilayers as determined from the deviation from equilibrium between pyrene monomers and excimers. J Biol Chem 271: 3085-3090, 1996.

3. BREIER A, ZIEGELHÖFFER A, STANKOVIČOVÁ T, DOČOLOMANSKÝ P, GEMEINER P, VRBANOVÁ A: Inhibition of (Na,K)-ATPase by electrophilic substances: functional implications. Mol Cell Biochem 147: 193-196, 1995.

4. CAGALINEC M, KYSELOVIC J, BLASKOVA E, BACHAROVA L, CHORVAT D Jr, CHORVATOVA A: Comparative study of the effects of lacidipine and enalapril on the left ventricular cardiomyocyte remodeling in spontaneously hypertensive rats. J Cardiovasc Pharmacol 47: 561-570, 2006.

5. ČÁRSKY J, LAZAROVÁ M, BEŇO A: Study of resorcylidene aminoguanidine. I. Spectral and acid-basic properties of the onium compounds. Acta Fac Rerum Nat Univ Comen Chimia 26: 89-102, 1978.

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