Abstract
Osteoporosis is a systemic disease of the skeleton, characterized
by reduction of bone mass and concurrent deterioration of bone
structure. Consequently, bones are more fragile, and there is
increased risk of fractures. The potential for acquisition of
maximum bone mass is influenced by a number of factors.
Among those are heredity, sex, nutrition, endocrine factors,
mechanical influences and some risk factors. The best
documented nutrient for metabolism of bone is calcium. Major
role in the pathogenesis of osteoporosis have some micro and
macro nutrients, prebiotics, alcohol, alternative diets, starvation
and anorexia. Meta analysis of 29 randomized trials showed that
supplementation with calcium and vitamin D3 reduces risk of
bone fractures by 24 % and significantly reduces loss of bone
mass. Osteoporosis has multi factor etiology. Osteoporosis is one
of diseases which are influenced by nutrition and life style. It is
preventable by means of adequate nutrition and sufficient
physical activity.
Publisher
Institute of Physiology of the Czech Academy of Sciences
Subject
General Medicine,Physiology
Cited by
31 articles.
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