Author:
Грынчак В.П.,Батян Г.М.,Сукало А.В.
Abstract
В статье представлены современные сведения о болезни (синдроме) Кавасаки у детей. Проведен анализ доступных литературных данных об этиологии, патогенезе, эпидемиологии, диагностике, клинических признаках, принципах терапии и динамического наблюдения за пациентами с данной патологией. Особое внимание уделено генетическим факторам, предрасполагающим к болезни Кавасаки. Представлена клиническая картина болезни с подробным описанием основных и дополнительных симптомов. Освещены проблемы развития осложнений со стороны сердечно-сосудистой системы в виде формирования аневризм и тромбозов коронарных сосудов в связи с поздней постановкой диагноза и неадекватной терапией. Изучен эффект от внутривенного введения иммуноглобулина в сочетании с ацетилсалициловой кислотой.
The article provides modern information about the Kawasaki disease (syndrome) in children. The analysis of available literature data on the etiology, pathogenesis, epidemiology, diagnosis, clinical signs, and principles of therapy and dynamic monitoring of patients with this pathology is carried out. Particular attention is paid to genetic factors that predispose to Kawasaki disease. The clinical picture of the disease is presented with a detailed description of the main and additional symptoms. The problems of the development of complications from the cardiovascular system in the form of aneurysms and thrombosis of the coronary vessels in connection with the late diagnosis and lack of adequate therapy are raised. The effect of intravenous administration of immunoglobulin in combination with acetylsalicylic acid is studied.
Publisher
Professionals Publications
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