PREDITORES PARA A PERSISTÊNCIA DE SINTOMAS NEUROLÓGICOS DA COVID-19 UM ANO APÓS O DIAGNÓSTICO: Estudo de coorte

Author:

Araujo Gustavo BaroniORCID,Peres Maria Ângela de Oliveira,Peres Caio Vinícius de Oliveira,Laskovski LarissaORCID,Felcar Josiane Marques,Trelha Celita SalmasoORCID,Junior Helio SerassueloORCID,Fillis Michelle Moreira Abujamra

Abstract

Knowledge about the frequency and predictive variables of persistent neurological manifestations associated with COVID-19 can contribute to directing the best treatment and recovery. The objective of this study was to identify the risk factors for the persistence of neurological symptoms (NSP) one year after the diagnosis of COVID-19. This is prospective research, carried out using a questionnaire sent to participants one month and one year after the diagnosis of COVID-19. To identify PSN risk factors after one year of diagnosis, the frequency of data relating to: sex; age; race/color; education; hospitalization; comorbidities and functional status present after 1 month and neurological symptoms (fatigue, headache, body pain, ageusia, anosmia, discouragement, irritability/mental confusion) present after one month and one year of diagnosis. Bivariate, multivariate and regression analyzes were performed. 379 patients with the following characteristics participated: age: median of 37 (29-49) years; color/race: white (69.1%); gender: female (64.9%); education: higher education (63.1%); hospitalized (9.2%); comorbidities: (33.24%), (13.7% - obesity). Regarding functional status: 55.1% altered; neurological symptoms after one month and after one year, respectively: frequency (57.5%), (38.5%), fatigue (30.3%), (19%) respectively. The predictor variables for PSN one year after diagnosis were comorbidities (P<0.003), changes in functional status and/or neurological symptoms one month after diagnosis: (P<0.001), respectively. One year after diagnosis, 38.5% presented persistent neurological symptoms, with a prevalence of fatigue (19.0%), and the risk factors were the presence of comorbidity, neurological symptoms and changes in functional status one month after diagnosis.

Publisher

Psicologia e Saude em Debate

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