Author:
Oldmeadow Christopher,Mengersen Kerrie,Martin Nicholas,Duffy David L.
Abstract
AbstractAppendicitis usually afflicts the young, but there is a large tail in the distribution of onset age. The genetics of this disease are still not well understood. A heritability analysis and genome wide linkage analysis of a large twin dataset was undertaken. Treating age of onset of appendicitis as a censored survival trait revealed a heritability of 0.21, and found evidence of linkage to Chromosome 1p37.3.
Publisher
Cambridge University Press (CUP)
Subject
Genetics (clinical),Obstetrics and Gynecology,Pediatrics, Perinatology and Child Health
Cited by
11 articles.
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