Abstract
Various methods of frequent pattern mining have been applied to genetic problems, specifically, to the combined association of two genotypes (a genotype pattern, or diplotype) at different DNA variants with disease. These methods have the ability to come up with a selection of genotype patterns that are more common in affected than unaffected individuals, and the assessment of statistical significance for these selected patterns poses some unique problems, which are briefly outlined here.
Publisher
Korea Genome Organization
Subject
Health Informatics,Genetics,Ecology, Evolution, Behavior and Systematics
Cited by
3 articles.
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