Evaluating Human Embryonic Germ Cells: Concord and Conflict as Pluripotent Stem Cells-Reference-Cited by-同舟云学术

Evaluating Human Embryonic Germ Cells: Concord and Conflict as Pluripotent Stem Cells

Published:2005-09-06 Issue:2 Volume:24 Page:212-220
ISSN:1066-5099
Container-title:Stem Cells
language:en
Short-container-title:

Author:

Turnpenny Lee¹²,Spalluto Cosma M.¹²,Perrett Rebecca M.¹²,O'Shea Marie¹²,Hanley Karen Piper¹²,Cameron Iain T.¹³,Wilson David I.¹²,Hanley Neil A.¹²

Affiliation:

1. Early Human Development and Stem Cells Group, University of Southampton, Southampton General Hospital, Southampton, United Kingdom

2. Human Genetics Division, University of Southampton, Southampton General Hospital, Southampton, United Kingdom

3. Developmental Origins of Health and Disease Division, University of Southampton, Southampton General Hospital, Southampton, United Kingdom

Abstract

Abstract The realization of cell replacement therapy derived from human pluripotent stem cells requires full knowledge of the starting cell types as well as their differentiated progeny. Alongside embryonic stem cells, embryonic germ cells (EGCs) are an alternative source of pluripotent stem cell. Since 1998, four groups have described the derivation of human EGCs. This review analyzes the progress on derivation, culture, and differentiation, drawing comparison with other pluripotent stem cell populations.

Publisher

Oxford University Press (OUP)

Subject

Cell Biology,Developmental Biology,Molecular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1634/stemcells.2005-0255

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