Affiliation:
1. Cellular Reprogramming Laboratory; Centro de Investigación Príncipe Felipe (CIPF), Valencia, Spain
Abstract
Abstract
Human embryonic stem cells (hESCs) are self-renewing pluripotent cells that have the capacity to differentiate into a wide variety of cell types. This potentiality represents a promising source to overcome many human diseases by providing an unlimited supply of all cell types, including cells with neural characteristics. Therefore, this review summarizes early neural development and the potential of hESCs to differentiate under in vitro conditions, examining at the same time the potential use of differentiated hESCs for therapeutic applications for neural tissue and cell regeneration.
Funder
Regional Government Health Department
Instituto Carlos III belonging to the Spanish Ministry of Health and Consumer Affairs
Spanish Ministry of Education and Science
Publisher
Oxford University Press (OUP)
Subject
Cell Biology,Developmental Biology,Molecular Medicine
Cited by
108 articles.
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