Safety Update on Erythropoiesis-Stimulating Agents: Trials Within and Outside the Accepted Indications-Reference-Cited by-同舟云学术

Safety Update on Erythropoiesis-Stimulating Agents: Trials Within and Outside the Accepted Indications

Published:2008-05-01 Issue:S3 Volume:13 Page:4-10
ISSN:1083-7159
Container-title:The Oncologist
language:en
Short-container-title:

Author:

Gascón Pere¹

Affiliation:

1. Medical Oncology, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain

Abstract

Abstract Certain studies in which erythropoiesis-stimulating agents (ESAs) have been given not with the aim of correcting anemia but to achieve higher target levels of hemoglobin have shown significantly poorer survival among treated patients. However, studies in which ESAs were administered with the aim of reducing the need for RBC transfusions in patients with chemotherapy-associated anemia demonstrate that the use of these agents is not associated with any adverse effect on survival when compared with placebo controls. We can therefore be reassured that using ESAs within the labeled indications will not adversely affect patient outcome.

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Oncology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1634/theoncologist.13-S3-4

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