A Practical Update on the Use of Bortezomib in the Management of Multiple Myeloma

Author:

San Miguel Jesús1,Bladé Joan2,Boccadoro Mario3,Cavenagh Jamie4,Glasmacher Axel5,Jagannath Sundar6,Lonial Sagar7,Orlowski Robert Z.8,Sonneveld Pieter9,Ludwig Heinz10

Affiliation:

1. a Hospital Clinico Universitario de Salamanca, Salamanca, Spain

2. b Institut d'Investigacions Biomédiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain

3. c University of Turin, Turin, Italy

4. d St. Bartholomew's Hospital, London, United Kingdom

5. e University of Bonn, Bonn, Germany

6. f St Vincent's Comprehensive Cancer Center, New York, New York, USA

7. g Winship Cancer Institute, Atlanta, Georgia, USA

8. h Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina, USA

9. i Virchow-University Hospital, Berlin, Germany

10. j Erasmus Medical Center, Rotterdam, The Netherlands

Abstract

Learning Objectives After completing this course, the reader will be able to: Discuss clinical trial data for treatment with bortezomib monotherapy and bortezomib-based combination therapy in patients with multiple myeloma who have received at least one prior therapy.Discuss the management of the most common adverse events associated with bortezomib, including peripheral neuropathy and thrombocytopenia.Describe prognostic factors in patients with multiple myeloma who have received at least one prior therapy. Access and take the CME test online and receive 1 AMA PRA category 1 credit at CME.TheOncologist.com

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Oncology

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