Alternating Chemotherapy and Radiotherapy in Locally Advanced Head and Neck Cancer: An Alternative?

Author:

Merlano Marco1

Affiliation:

1. Department of Clinical Oncology, S. Croce General Hospital, Cuneo, Italy

Abstract

Learning Objectives After completing this course, the reader will be able to: Discuss the results of trials with alternating chemotherapy and radiotherapy for the treatment of locoregionally advanced head and neck cancer.Describe the rationale for using alternating chemotherapy and radiotherapy in the management of head and neck cancer.Explain why chemoradiation should preferably be managed by an experienced staff.Assess the role played by different drugs in the development of mucositis in an alternating chemotherapy and radiotherapy combined treatment. CME Access and take the CME test online and receive 1 AMA PRA category 1 credit at CME.TheOncologist.com

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Oncology

Reference30 articles.

1. Treatment of advanced squamous-cell carcinoma of the head and neck with alternating chemotherapy and radiotherapy;Merlano;N Engl J Med,1992

2. Concurrent chemoradiation in the treatment of head and neck cancer;Haffty;Hematol Oncol Clin North Am,1999

3. Alternation of chemotherapy and radiotherapy in cancer management. III. Results in experimental solid tumor systems and their relationship to clinical studies;Looney;Cancer Treat Rep,1986

4. Chemotherapy added to locoregional treatment for head and neck squamous cell carcinoma: three meta-analyses of updated individual data;Pignon;Lancet,2000

5. Radiochemotherapy in head and neck cancer;Merlano;Cancer Treat Rev,2003

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