1. a Division of Clinical Pharmacology, Department of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands
2. b Department of Experimental Therapy, The Netherlands Cancer Institute, Amsterdam, The Netherlands
3. c Department of Gastroenterology and Hepatology, The Netherlands Cancer Institute, Amsterdam, The Netherlands;
4. d Slotervaart Hospital, Department of Pharmacy & Pharmacology, Amsterdam, The Netherlands;
5. e Faculty of Science, Department of Pharmaceutical Sciences, Section of Biomedical Analysis, Division of Drug Toxicology, Utrecht University, Utrecht, The Netherlands