Neoadjuvant Paradigm for Accelerated Drug Development: An Ideal Model in Bladder Cancer-Reference-Cited by-同舟云学术

Neoadjuvant Paradigm for Accelerated Drug Development: An Ideal Model in Bladder Cancer

Published:2013-07-24 Issue:8 Volume:18 Page:933-940
ISSN:1083-7159
Container-title:The Oncologist
language:en
Short-container-title:

Author:

Chism David D.¹,Woods Michael E.²,Milowsky Matthew I.¹

Affiliation:

1. Department of Medicine, Division of Hematology and Oncology, Chapel Hill, North Carolina, USA

2. Department of Surgery, Division of Urologic Surgery, University of North Carolina at Chapel Hill Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina, USA

Abstract

Learning Objectives Describe how pathological complete response predicts for improved outcome in patients with MIBC. Explain the biological rationale for neoadjuvant chemotherapy in MIBC related to the dysregulation in PI3K/AKT, RAF/MEK/ERK signaling pathways, and ERBb family.

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Oncology

Link

https://pericles-gcp.literatumonline.com/doi/pdf/10.1634/theoncologist.2013-0023

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