Immunotherapy for Head and Neck Squamous Cell Carcinoma: A Review of Current and Emerging Therapeutic Options-Reference-Cited by-同舟云学术

Immunotherapy for Head and Neck Squamous Cell Carcinoma: A Review of Current and Emerging Therapeutic Options

Published:2017-05-15 Issue:6 Volume:22 Page:680-693
ISSN:1083-7159
Container-title:The Oncologist
language:en
Short-container-title:

Author:

Moskovitz Jessica M.¹,Moy Jennifer¹,Seiwert Tanguy Y.²³,Ferris Robert L.¹⁴⁵

Affiliation:

1. Department of Otolaryngology University of Pittsburgh, Pittsburgh, Pennsylvania, USA

2. Department of Medicine, Hematology/Oncology University of Chicago, Chicago, Illinois, USA

3. The University of Chicago Comprehensive Cancer Center, Chicago, Illinois, USA

4. Department of Immunology University of Pittsburgh, Pittsburgh, Pennsylvania, USA

5. Cancer Immunology Program, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, USA

Abstract

Abstract Advances in the field of cancer immunotherapy have occurred rapidly over the past decade. Exciting results from clinical trials have led to new treatment options and improved survival for patients with a myriad of solid tumor pathologies. However, questions remain unanswered regarding duration and timing of therapy, combination regimens, appropriate biomarkers of disease, and optimal monitoring of therapeutic response. This article reviews emerging immunotherapeutic agents and significant clinical trials that have led to advancements in the field of immuno-oncology for patients with head and neck squamous cell carcinoma.

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Oncology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1634/theoncologist.2016-0318

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