Bevacizumab for Advanced Breast Cancer: Hope, Hype, and Hundreds of Headlines

Author:

Fralick Michael1,Ray Monali2,Fung Christina2,Booth Christopher M.3,Mallick Ranjeeta4,Clemons Mark J.5

Affiliation:

1. Department of Medicine, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada;

2. Department of Medicine, University of Toronto, Toronto, Ontario, Canada;

3. Department of Oncology, Queen's University, Kingston, Ontario, Canada;

4. Ottawa Hospital Research Institute, Ottawa, Ontario, Canada;

5. Department of Medicine, The Ottawa Hospital Cancer Centre, University of Ottawa, Ottawa, Ontario, Canada

Abstract

Learning Objectives Summarize findings regarding the media's portrayal of bevacizumab with each phase of therapeutic development. Identify media sources of information about bevacizumab in each phase of therapeutic development.

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Oncology

Reference25 articles.

1. Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer;Miller;N Engl J Med,2007

2. RIBBON-1: Randomized, double-blind, placebo-controlled, phase III trial of chemotherapy with or without Bevacizumab for first-line treatment of human epidermal growth factor receptor 2-negative, locally recurrent or metastatic breast cancer;Robert;J Clin Oncol,2011

3. Final overall survival (OS) results from the randomised, double-blind, placebo-controlled, phase III AVADO study of bevacizumab (BV) plus docetaxel (D) compared with placebo (PL) plus D for the first-line treatment of locally recurrent (LR) or metastatic breast cancer (mBC);Miles;Cancer Res,2009

4. Drugs in the news: An analysis of Canadian newspaper coverage of new prescription drugs;Cassels;CMAJ,2003

5. Reporting research in medical journals and newspapers;Entwistle;BMJ,1995

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