Fertility-Sparing Treatment of Endometrial Cancer with Initial Infiltration of Myometrium by Resectoscopic Surgery: A Pilot Study

Author:

Casadio Paolo1,Guasina Francesca1,Paradisi Roberto1,Leggieri Concetta1,Caprara Giacomo2,Seracchioli Renato1

Affiliation:

1. Department of Obstetrics, Gynecology, and Reproductive Biology, University Alma Mater Studiorum of Bologna, Bologna, Italy

2. Department of Pathology, DIMEC, S. Orsola Hospital, University Alma Mater Studiorum of Bologna, Bologna, Italy

Abstract

Abstract Three women with a well-differentiated grade 1 endometrioid adenocarcinoma of the endometrium with minimal myometrial infiltration were treated with hysteroscopic resection and hormone therapy. The presence of myometrial infiltration has often been mentioned as an exclusion criterion for conservative management in young patients because of worsening cancer prognosis. The subsequent 5-year follow-up and the pregnancies achieved may confirm the choice of this temporary treatment and indicate a new option for fertility-sparing treatment in highly motivated patients.

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Oncology

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