The Relationship Between Eight GWAS-Identified Single-Nucleotide Polymorphisms and Primary Breast Cancer Outcomes-Reference-Cited by-同舟云学术

The Relationship Between Eight GWAS-Identified Single-Nucleotide Polymorphisms and Primary Breast Cancer Outcomes

Published:2013-05-01 Issue:5 Volume:18 Page:493-500
ISSN:1083-7159
Container-title:The Oncologist
language:en
Short-container-title:

Author:

Bayraktar Soley¹,Thompson Patricia A.²,Yoo Suk-Young³,Do Kim-anh³,Sahin Aysegul A.⁴,Arun Banu K.⁵,Bondy Melissa L.⁶,Brewster Abenaa M.⁷

Affiliation:

1. Department of Medical Oncology, Mercy Cancer Center, Ardmore, Oklahoma, USA;

2. Department of Cellular and Molecular Medicine, Arizona Cancer Center, University of Arizona, Tucson, Arizona, USA;

3. Department of Biostatistics, Cancer Prevention and Population Sciences, Houston, Texas, USA

4. Department of Pathology, Cancer Prevention and Population Sciences, Houston, Texas, USA

5. Department of Breast Medical Oncology, Cancer Prevention and Population Sciences, Houston, Texas, USA

6. Baylor College of Medicine, Cancer Prevention and Population Sciences, Houston, Texas, USA

7. Department of Clinical Cancer Prevention, University of Texas MD Anderson Cancer Center, Houston, Texas, USA;

Abstract

Learning Objectives Describe the results of genome-wide association studies (GWAS) that have identified genetic variants associated with breast cancer risk. Discuss whether genetic risk variants identified through genome-wide association studies (GWAS) are also associated with breast cancer prognosis. Describe molecular mechanisms through which germline genetic variants may influence breast cancer survival.

Funder

National Cancer Institute

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Oncology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1634/theoncologist.2012-0419

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