Renal Cell Carcinoma: New Developments in Molecular Biology and Potential for Targeted Therapies

Author:

Costa Luciano J.1,Drabkin Harry A.2

Affiliation:

1. a University of Colorado Health Sciences Center, Denver, Colorado, USA

2. b Medical University of South Carolina, Division of Hematology-Oncology, Charleston, South Carolina, USA

Abstract

Learning Objectives After completing this course, the reader will be able to: List the most frequent genetic abnormalities involved in RCC and explain how they lead to abnormal response to hypoxia, cell survival, and angiogenesis.Interpret the current literature concerning the treatment of RCC, and correlate therapeutic agents with their targets and underlying biological processes that drive the disease.Identify the limitations of current agents used in the treatment of RCC and the challenges that need to be overcome in developing therapies to improve the outcome of patients with advanced disease. Access and take the CME test online and receive 1 AMA PRA Category 1 Credit™ at CME.TheOncologist.com

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Oncology

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