Glucarpidase (Carboxypeptidase G2) Intervention in Adult and Elderly Cancer Patients with Renal Dysfunction and Delayed Methotrexate Elimination After High-Dose Methotrexate Therapy-Reference-Cited by-同舟云学术

Glucarpidase (Carboxypeptidase G2) Intervention in Adult and Elderly Cancer Patients with Renal Dysfunction and Delayed Methotrexate Elimination After High-Dose Methotrexate Therapy

Published:2007-11-01 Issue:11 Volume:12 Page:1299-1308
ISSN:1083-7159
Container-title:The Oncologist
language:en
Short-container-title:

Author:

Schwartz Stefan¹,Borner Klaus²,Müller Krystina¹,Martus Peter³,Fischer Lars¹,Korfel Agnieszka¹,Auton Timothy⁴,Thiel Eckhard¹

Affiliation:

1. a Medizinische Klinik III, Charité, Campus Benjamin Franklin, Berlin, DEGermany

2. b Institut für Klinische Chemie und Pathobiochemie, Charité, Campus Benjamin Franklin, Berlin, DEGermany

3. c Institut für Biometrie und Klinische Epidemiologie, Charité, Campus Benjamin Franklin, Berlin, DEGermany

4. d Protherics PLC, Runcorn, United Kingdom

Abstract

Learning Objectives After completing this course, the reader will be able to: Identify risk factors for kidney failure associated with high-dose MTX therapy.Discuss the therapeutic options in patients with delayed MTX elimination.Discuss the potential risks and benefits of glucarpidase intervention. Access and take the CME test online and receive 1 AMA PRA Category 1 Credit™ at CME.TheOncologist.com

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Oncology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1634/theoncologist.12-11-1299

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