Amifostine: The First Selective-Target and Broad-Spectrum Radioprotector

Author:

Kouvaris John R.1,Kouloulias Vassilis E.2,Vlahos Lampros J.1

Affiliation:

1. Aretaieion Hospital University of Athens, Athens, Greece

2. Attikon Hospital University of Athens, Athens, Greece

Abstract

Learning Objectives After completing this course, the reader will be able to: Select appropriate multidisciplinary treatment regimens and cytoprotection for clinical trials for patients with head and neck cancer.Identify radiation toxicity for the head and neck, lung, and pelvic irradiated areas.Describe the cytoprotective effect of amifostine against radiation toxicity. CME Access and take the CME test online and receive 1 AMA PRA Category 1 Credit™ at CME.TheOncologist.com

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Oncology

Reference64 articles.

1. Effects of radiation on normal tissue: Consequences and mechanisms;Stone;Lancet Oncol,2003

2. Differential chemoprotection of normal and malignant tissues;Yuhas;J Natl Cancer Inst,1969

3. American Society of Clinical Oncology clinical practice guidelines for the use of chemotherapy and radiotherapy protectants;Hensley;J Clin Oncol,1999

4. Amifostine: Is there evidence of tumor protection?;Koukourakis;Semin Oncol,2003

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