Improved Insight into Resistance Mechanisms to Imatinib in Gastrointestinal Stromal Tumors: A Basis for Novel Approaches and Individualization of Treatment-Reference-Cited by-同舟云学术

Improved Insight into Resistance Mechanisms to Imatinib in Gastrointestinal Stromal Tumors: A Basis for Novel Approaches and Individualization of Treatment

Published:2007-06-01 Issue:6 Volume:12 Page:719-726
ISSN:1083-7159
Container-title:The Oncologist
language:en
Short-container-title:

Author:

Sleijfer Stefan¹,Wiemer Erik¹,Seynaeve Caroline¹,Verweij Jaap¹

Affiliation:

1. Department of Medical Oncology, Erasmus University Medical Centre, Daniel den Hoed Cancer Centre, Rotterdam, The Netherlands

Abstract

Learning Objectives After completing this course, the reader will be able to: Describe the most important resistance mechanisms to imatinib that are responsible for early and late progression.Discuss the most important systemic treatment options for managing progressive disease under imatinib treatment.Explain how insight into mechanisms conferring sensitivity to imatinib may be used to individualize treatment of patients presenting with GIST. CME Access and take the CME test online and receive 1 AMA PRA Category 1 Credit™ at CME.TheOncologist.com

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Oncology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1634/theoncologist.12-6-719

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