Erlotinib in Non-Small Cell Lung Cancer Treatment: Current Status and Future Development

Author:

Gridelli Cesare1,Bareschino Maria Anna2,Schettino Clorinda2,Rossi Antonio1,Maione Paolo1,Ciardiello Fortunato2

Affiliation:

1. a Division of Medical Oncology, “S.G. Moscati” Hospital, Avellino, Italy

2. b Division of Medical Oncology, Department of Clinical and Experimental Medicine and Surgery “F. Magrassi and A. Lanzara,” Second University of Naples, School of Medicine, Naples, Italy

Abstract

Learning Objectives After completing this course, the reader will be able to: Describe the molecular mechanism of action of erlotinib.Define clinical and molecular predictors of response to erlotinib.Describe the clinical trials performed with erlotinib in NSCLC and underline future clinical development of this drug in the treatment of NSCLC. CME Access and take the CME test online and receive 1 AMA PRA Category 1 Credit™ at CME.TheOncologist.com

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Oncology

Reference56 articles.

1. Twenty-two years of phase III trials for patients with advanced non-small-cell lung cancer: Sobering results;Breathnach;J Clin Oncol,2001

2. Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer;Schiller;N Engl J Med,2002

3. Target-based agents against ErbB receptors and their ligands: A novel approach to cancer treatment;Normanno;Endocr Relat Cancer,2003

4. Blockade of receptors for growth factor: An anticancer therapy – the fourth annual Joseph H Burchenal American Association of Cancer Research Clinical Research Award Lecture;Mendelsohn;Clin Cancer Res,2000

5. The ErbB signaling network: Receptor heterodimerization in development and cancer;Olayioye;EMBO J,2000

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