First-Line Treatment Options for Patients with HER-2–Negative Metastatic Breast Cancer: The Impact of Modern Adjuvant Chemotherapy

Author:

Verma Sunil1,Clemons Mark2

Affiliation:

1. a Division of Medical Oncology, Sunnybrook and Women's College Health Sciences Centre, Toronto, Canada

2. b Princess Margaret Hospital, Toronto, Canada

Abstract

Learning Objectives After completing this course, the reader will be able to: Describe how changes in adjuvant treatment are having a major influence on treatment options in the first-line setting for metastatic breast cancer.Select the most appropriate first-line treatment for a patient with metastatic breast cancer based on previous adjuvant therapy.Discuss how as treatment options become more complex, there may no longer be a single “gold standard” therapy, and a variety of factors must be considered when selecting therapy. CME Access and take the CME test online and receive 1 AMA PRA Category 1 Credit™ at CME.TheOncologist.com

Funder

Medi-Kelsey Limited

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Oncology

Reference76 articles.

1. Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: An overview of the randomised trials;Early Breast Cancer Trialists' Collaborative Group (EBCTCG);Lancet,2005

2. Paclitaxel after doxorubicin plus cyclophosphamide as adjuvant chemotherapy for node-positive breast cancer: Results from NSABP B-28;Mamounas;J Clin Oncol,2005

3. Improved outcomes from adding sequential paclitaxel but not from escalating doxorubicin dose in an adjuvant chemotherapy regimen for patients with node-positive primary breast cancer;Henderson;J Clin Oncol,2003

4. Five years analysis of the PACS 01 trial: 6 cycles of FEC100 vs 3 cycles of FEC100 followed by 3 cycles of docetaxel (D) for the adjuvant treatment of node positive breast cancer;Roché;Breast Cancer Res Treat,2004

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3