Steroid Sulfatase: A New Target for the Endocrine Therapy of Breast Cancer-Reference-Cited by-同舟云学术

Steroid Sulfatase: A New Target for the Endocrine Therapy of Breast Cancer

Published:2007-04-01 Issue:4 Volume:12 Page:370-374
ISSN:1083-7159
Container-title:The Oncologist
language:en
Short-container-title:

Author:

Stanway Susannah J.¹,Delavault Patrick²,Purohit Atul¹,Woo L. W. Lawrence³,Thurieau Christophe²,Potter Barry V. L.³,Reed Michael J.¹

Affiliation:

1. a Endocrinology and Metabolic Medicine and Sterix Ltd., Imperial College, St. Mary's Hospital, London, United Kingdom

2. b Ipsen, Institute Henri Beaufour, Les Ulis, France

3. c Medicinal Chemistry, Department of Pharmacy and Pharmacology and Sterix Ltd., University of Bath, Bath, United Kingdom

Abstract

Learning Objectives After completing this course, the reader will be able to: Discuss the role of steroid sulfatase in regulating estrogen production in postmenopausal women.Describe the potential of steroid sulfatase inhibition in cancer therapy.Discuss a potential new endocrine therapy for patients progressing on aromatase. CME Access and take the CME test online and receive 1 AMA PRA Category 1 Credit™ at CME.TheOncologist.com

Funder

Sterix

Ipsen Group

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Oncology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1634/theoncologist.12-4-370

Reference27 articles.

1. Aromatase activity and interleukin-6 production by normal and malignant breast tissues;Purohit;J Clin Endocrinol Metab,1995

2. Breast cancer and the role of cytokines in regulating estrogen synthesis: An emerging hypothesis;Reed;Endocr Rev,1997