SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL SCREENING OF SOME NEW ISOXAZOLE DERIVATIVES INCORPORATING 6, 8-DIBROMO-2-METHYLQUINAZOLIN-4-ONE MOIETY-Reference-Cited by-同舟云学术

SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL SCREENING OF SOME NEW ISOXAZOLE DERIVATIVES INCORPORATING 6, 8-DIBROMO-2-METHYLQUINAZOLIN-4-ONE MOIETY

Published:2022-06-30 Issue: Volume: Page:525-535
ISSN:0974-035X
Container-title:Towards Excellence
language:en
Short-container-title:Towards Excell.

Author:

Savaliya Komal R¹

Affiliation:

1. Centre of Education, Indian Institute of Teacher Education, Gandhinagar

Abstract

A novel series of 6,8-dibromo-3-[4-(5-substitutedphenyl-1,2-oxazol-3-yl)phenyl]-2-methylquinazolin-4-one have been synthesized by refluxation of 6,8-dibromo-3-{4-[3-(substitutedphenyl)prop-2-enoyl]phenyl}-2-methylquinazolin-4-one in dioxane, hydroxylamine hydrochloride and potassium hydroxide (KOH). The chemical structures of the synthesized compounds have been confirmed by IR, NMR and spectral data and evaluated for antibacterial and antifungal activity.

Publisher

Gujarat University

Subject

General Medicine

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