Author:
Reddy A.P.,Sunitha R.,Thangavel P.,Ramkumar J.,Miller S.G.
Abstract
Cardiopulmonary bypass (CPB) might have several systemic impacts on organs such as the liver. This prospective research was designed to investigate the occurrence & significance of this shift in more depth.40 patients of cardiopulmonary bypass were chosen at random for the research. After coronary artery bypass grafting, total bilirubin, direct bilirubin, Alkaline Phosphatase (ALP), SGOT, & SGPT were determined preoperatively & post operation after 24, 48 hours. The liver function tests’ (LFT) post-operative value, in relation to above factors, was compared with preoperative value using t test. The results show a statistically significant increase (p ≤ 0.05) in total bilirubin, direct bilirubin, Alkaline Phosphatase, SGOT, & SGPT on post-operative days 1 & 2 in patients who had complex surgeries & valve replacement surgeries while on CPB. Low cardiac output may be related with a transient rise in hepatic enzyme levels following surgery. Throughout the post-operative period, hepatic enzyme levels were higher in patients with longer CPB durations.
Subject
General Medicine,Linguistics and Language,Language and Linguistics,Education,General Decision Sciences,Public Health, Environmental and Occupational Health,Orthopedics and Sports Medicine,Physical Therapy, Sports Therapy and Rehabilitation,Education,General Medicine,General Medicine,General Physics and Astronomy,Cell Biology,Plant Science,Molecular Biology,Biochemistry,Biotechnology
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