A case of chemotherapy efficacy with atezolizumab plus bevacizumab dose reduction for hepatocellular carcinoma against nasal hemorrhage as bevacizumab-related adverse event
Author:
Affiliation:
1. Department of Hepato-biliary-pancreatic Medicine, Saiseikai Fukuoka General Hospital
Publisher
Japan Society of Hepatology
Link
https://www.jstage.jst.go.jp/article/kanzo/65/1/65_31/_pdf
Reference9 articles.
1. 1) 一般社団法人日本肝臓学会編, 「肝癌診療ガイドライン (2021年版)」金原出版, 東京, 2021
2. 2) Garcia J, Hurwitz HI, Sandler AB, et al. Bevacizumab (Avastin®) in cancer treatment: A review of 15 years of clinical experience and future outlook. Cancer Treat Rev 2020; 86: 102017
3. 3) Finn RS, Qin S, Ikeda M, et al. Atezolizumab plus Bevacizumab in Unresectable Hepatocellular Carcinoma. N Engl J Med 2020; 382: 1894-1905
4. 4) Lee SP, Hsu HC, Tai YJ, et al. Bevacizumab dose affects the severity of adverse events in gynecologic malignancies. Front Pharmacol 2019; 10: 426
5. 5) Zhu X, Wu S, Dahut WL, et al. Risks of proteinuria and hypertension with bevacizumab, an antibody against vascular endothelial growth factor: systematic review and meta-analysis. Am J Kidney Dis 2007; 49: 186-193
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