Long-term sustained complete response with off-therapy to sorafenib in advanced hepatocellular carcinoma: a case report
Author:
Affiliation:
1. Department of Surgery, Himeji Red Cross Hospital
2. Department of Internal Medicine, Himeji Red Cross Hospital
Publisher
Japan Society of Hepatology
Subject
Hepatology
Link
https://www.jstage.jst.go.jp/article/kanzo/61/5/61_255/_pdf
Reference30 articles.
1. 1) Kudo M, Finn RS, Qin S, et al. Lenvatinib versus sorafenib in first-line treatment of patients with unresectable hepatocellular carcinoma: a randomised phase 3 non-inferiority trial. The Lancet 2018; 391: 1163-1173
2. 2) Llovet JM, Ricci S, Mazzaferro V, et al. Sorafenib in advanced hepatocellular carcinoma. N Engl J Med 2008; 359: 378-390
3. 3) Cheng AL, Kang YK, Chen Z, et al. Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial. The Lancet Oncology 2009; 10: 25-34
4. 4) Shiba S, Okusaka T, Ikeda M, et al. Characteristics of 18 patients with hepatocellular carcinoma who obtained a complete response after treatment with sorafenib. Hepatol Res 2014; 44: 1268-1276
5. 5) Rimola J, Díaz-González Á, Darnell A, et al. Complete response under sorafenib in patients with hepatocellular carcinoma: Relationship with dermatologic adverse events. Hepatology 2018; 67: 612-622
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