A Possible New Mechanism in the Pathophysiology of Polycystic Ovary Syndrome (PCOS): The Discovery That Leukocyte Telomere Length Is Strongly Associated With PCOS

Author:

Li Qiaoli12,Du Jing3,Feng Ruizhi12,Xu Yao12,Wang Haojue12,Sang Qing12,Xing Qinghe2,Zhao Xinzhi2,Jin Li1,He Lin24,Wang Lei12

Affiliation:

1. State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology (Q.L., R.F., Y.X., H.W., Q.S., L.J., L.W.), School of Life Sciences, Fudan University, Shanghai, 200032, China

2. Institutes of Biomedical Sciences (Q.L., R.F., Y.X., H.W., Q.S., Q.X., X.Z., L.H., L.W.), Fudan University, Shanghai, 200032, China

3. NPFPC Laboratory of Contraception and Devices, Shanghai Institute of Planned Parenthood Research (J.D.), Shanghai 200032, China

4. Bio-X Center (L.H.), Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai, 200032, China

Publisher

The Endocrine Society

Subject

Biochemistry (medical),Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference47 articles.

1. Polycystic ovary syndrome;Ehrmann;N Engl J Med,2005

2. Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis;Dunaif;Endocr Rev,1997

3. Heritability of polycystic ovary syndrome in a Dutch twin-family study;Vink;J Clin Endocrinol Metab,2006

4. Genetics of polycystic ovary syndrome: searching for the way out of the labyrinth;Diamanti-Kandarakis;Hum Reprod Update,2005

5. Genetic association studies in female reproduction: from candidate-gene approaches to genome-wide mapping;Zhao;Mol Hum Reprod,2013

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