Refining Calcium Test for the Diagnosis of Medullary Thyroid Cancer: Cutoffs, Procedures, and Safety

Author:

Mian Caterina1,Perrino Michela23,Colombo Carla23,Cavedon Elisabetta1,Pennelli Gianmaria4,Ferrero Stefano56,De Leo Simone23,Sarais Cristiano7,Cacciatore Chiara28,Manfredi Gloria Irene28,Verga Uberta23,Iacobone Maurizio9,De Pasquale Loredana10,Pelizzo Maria Rosa11,Vicentini Leonardo12,Persani Luca28,Fugazzola Laura23

Affiliation:

1. Endocrinology (C.M., E.C.), 35122 Padua, Italy

2. Departments of Clinical Sciences and Community Health (M.P., C.Co., S.D.L., U.V., L.F., C.Ca., G.I.M., L.P.), 20122 Milan, Italy

3. University of Milan, and Endocrine (M.P., C.Co., S.D.L., U.V., L.F.), 20122 Milan, Italy

4. Surgical Pathology and Cytopathology (G.P.), Units, Department of Medicine, 35122 Padua, Italy

5. Biomedical, Surgical, and Dental Sciences (S.F.), 20122 Milan, Italy

6. Division of Pathology (S.F.), 20122 Milan, Italy

7. Departments of Cardiologic, Thoracic, and Vascular Sciences (C.S.), 35122 Padua, Italy

8. Division of Endocrine and Metabolic Diseases (C.Ca., G.I.M., L.P.), Ospedale San Luca, IRCCS Istituto Auxologico Italiano, 20149 Milan

9. Minimally Invasive Endocrine Surgery Unit (M.I.), Department of Surgery, Oncology, and Gastroenterology, 35122 Padua, Italy

10. Endocrine Surgery Unit (L.D.P.), San Paolo Hospital, 20142 Milan, Italy

11. Surgery, Oncology, and Gastroenterology (M.R.P.), University of Padua, 35122 Padua, Italy

12. Endocrine Surgery (L.V.) Units, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ca' Granda, 20122 Milan, Italy

Publisher

The Endocrine Society

Subject

Biochemistry (medical),Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference21 articles.

1. New therapeutic approaches to treat medullary thyroid carcinoma;Schlumberger;Nat Clin Pract Endocrinol Metab,2008

2. Impact of routine measurement of serum calcitonin on the diagnosis and outcome of medullary thyroid cancer: experience in 10,864 patients with nodular thyroid disorders;Elisei;J Clin Endocrinol Metab,2004

3. Medullary thyroid cancer: management guidelines of the American Thyroid Association;American Thyroid Association Guidelines Task Force;Thyroid,2009

4. Stimulated calcitonin cut-offs by different tests;Fugazzola;Eur Thyroid J,2013

5. Cholecystokinin(CCK)-A and CCK-B/gastrin receptors in human tumors;Reubi;Cancer Res,1997

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