Growth Hormone Exposure as a Risk Factor for the Development of Subsequent Neoplasms of the Central Nervous System: A Report From the Childhood Cancer Survivor Study

Author:

Patterson Briana C.1,Chen Yan2,Sklar Charles A.3,Neglia Joseph4,Yasui Yutaka2,Mertens Ann1,Armstrong Gregory T.5,Meadows Anna6,Stovall Marilyn7,Robison Leslie L.5,Meacham Lillian R.1

Affiliation:

1. Department of Pediatrics (B.C.P., A.Mer., L.R.M.) Emory University/Aflac Cancer and Blood Disorders Center of Children's Healthcare of Atlanta, Atlanta, Georgia 30322;

2. Department of Public Health Sciences (Y.C., Y.Y.), University of Alberta, Edmonton, Alberta, Canada T6G 1C9;

3. Department of Pediatrics (C.A.S.), Memorial Sloan-Kettering Cancer Center, New York, New York 10065;

4. Department of Pediatrics (J.N.), University of Minnesota Medical School, Minneapolis, Minnesota 55454;

5. Department of Epidemiology and Cancer Control (G.T.A., L.L.R.), St Jude Children's Research Hospital, Memphis, Tennessee 38105;

6. Division of Oncology (A.Mea.), The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104;

7. Department of Radiation Physics (M.S.), The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030

Publisher

The Endocrine Society

Subject

Biochemistry, medical,Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference31 articles.

1. Endocrine and cardiovascular late effects among adult survivors of childhood brain tumors: Childhood Cancer Survivor Study;Gurney;Cancer,2003

2. Prevalence and risk factors of radiation-induced growth hormone deficiency in childhood cancer survivors: a systematic review;Mulder;Cancer Treat Rev,2009

3. Cranial irradiation and growth hormone neurosecretory dysfunction: a critical appraisal;Darzy;J Clin Endocrinol Metab,2007

4. Pathophysiology of radiation-induced growth hormone deficiency: efficacy and safety of GH replacement;Darzy;Growth Horm IGF Res,2006

5. Incidence of second neoplasm in childhood cancer survivors treated with GH: an analysis of GeNeSIS and HypoCCS;Woodmansee;Eur J Endocrinol,2013

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