Age- and Sex-Specific Reference Intervals Across Life Span for Insulin-Like Growth Factor Binding Protein 3 (IGFBP-3) and the IGF-I to IGFBP-3 Ratio Measured by New Automated Chemiluminescence Assays

Author:

Friedrich Nele1,Wolthers Ole D.2,Arafat Ayman M.345,Emeny Rebecca T.6,Spranger Joachim347,Roswall Josefine8,Kratzsch Jürgen9,Grabe Hans J.1011,Hübener Christoph12,Pfeiffer Andreas F. H.35,Döring Angela6,Bielohuby Maximilian13,Dahlgren Jovanna8,Frystyk Jan1415,Wallaschofski Henri1,Bidlingmaier Martin13

Affiliation:

1. Metabolic Center (N.F., H.W.), D-17475 Greifswald, Germany

2. Children's Clinic Randers (O.D.W.), DK-8900 Randers, Denmark

3. Department of Endocrinology, Diabetes, and Nutrition (A.M.A., J.S., A.F.H.P.), D-10117 Berlin, Germany

4. Center for Cardiovascular Research (A.M.A., J.S.), Charité-University Medicine Berlin, D-10117 Berlin, Germany

5. Department of Clinical Nutrition (A.M.A., A.F.H.P.), German Institute of Human Nutrition Potsdam-Rehbruecke, D-14558 Nuthetal, Germany

6. Helmholtz Zentrum Muenchen-German Research Center for Environmental Health (R.T.E., A.D.), Institute of Epidemiology II, D-85764 Neuherberg, Germany

7. Experimental and Clinical Research Center (J.S.), Charité-University Medicine Berlin and Max-Delbrück Centre Berlin-Buch, D-13125 Berlin, Germany

8. Göteborg Pediatric Growth Research Center (J.R., J.D.), The Sahlgrenska Academy at University of Gothenburg, SE-41685 Gothenburg, Sweden

9. Institut für Laboratoriumsmedizin (J.K.), Klinische Chemie, Molekulare Diagnostik, University of Leipzig, D-04103 Leipzig, Germany

10. Institute of Clinical Chemistry and Laboratory Medicine, and Department of Psychiatry and Psychotherapy (H.J.G.), University Medicine Greifswald, D-17475 Greifswald, Germany

11. Department of Psychiatry and Psychotherapy (H.J.G.), Helios Hospital Stralsund, D-18437 Stralsund, Germany

12. Klinik und Poliklinik für Frauenheilkunde und Geburtshilfe-Großhadern (C.H.), Klinikum der Universität München, D-81377 Munich, Germany

13. Endocrine Research Laboratories (M.B., M.B.), Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, D-80336 Munich, Germany

14. Medical Research Laboratory (J.F.), DK-8000 C Aarhus, Denmark

15. Department of Clinical Medicine, Faculty of Health, Aarhus University, and Department of Endocrinology and Internal Medicine (J.F.), Aarhus University Hospital, DK-8000 C Aarhus, Denmark

Publisher

The Endocrine Society

Subject

Biochemistry (medical),Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

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