A Paradigm Shift in the Monitoring of Patients With Acromegaly: Last Available Growth Hormone May Overestimate Risk

Author:

Sherlock Mark12,Reulen Raoul C.3,Aragon-Alonso Aurora1,Ayuk John14,Clayton Richard N.5,Sheppard Michael C.1,Hawkins Michael M.3,Bates Andrew S.6,Stewart Paul M.1

Affiliation:

1. Endocrinology, Diabetes, and Metabolism (M.S., A.A.-A., J.A., M.C.S., P.M.S.), Division of Medical Sciences, University of Birmingham, Birmingham B15 2TH, United Kingdom

2. Department of Endocrinology and Diabetes (M.S.), Adelaide and Meath Hospitals, Incorporating the National Children's Hospital and Trinity College, Dublin, Ireland

3. Centre for Childhood Cancer Survivor Studies (R.C.R., M.M.H.), School of Health and Population Sciences, Public Health Building, University of Birmingham, Birmingham B15 2TT, United Kingdom

4. Department of Endocrinology (J.A.), Queen Elizabeth Hospital Birmingham, Birmingham B152TH, United Kingdom

5. Department of Postgraduate Medicine (R.N.C.), University of Keele, Hartshill, Stoke-on-Trent ST4 7QB, United Kingdom

6. Birmingham Heartlands and Solihull National Health Service Trust (A.S.B.), Birmingham B9 5SS, United Kingdom

Publisher

The Endocrine Society

Subject

Biochemistry, medical,Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference33 articles.

1. Epidemiology of acromegaly in the Newcastle region;Alexander;Clin Endocrinol (Oxf),1980

2. Growth hormone and pituitary radiotherapy, but not serum insulin-like growth factor-I concentrations, predict excess mortality in patients with acromegaly;Ayuk;J Clin Endocrinol Metab,2004

3. An audit of outcome of treatment in acromegaly;Bates;Q J Med,1993

4. Long-term outcome and mortality after transsphenoidal adenomectomy for acromegaly;Beauregard;Clin Endocrinol (Oxf),2003

5. Factors influencing mortality in acromegaly;Holdaway;J Clin Endocrinol Metab,2004

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